Ancillary Tests & Services
BDL offers a comprehensive suite of Ancillary Tests and Services designed to enhance diagnostic precision and support personalized medicine. Our offerings include Immunohistochemistry (IHC), In Situ Hybridization (ISH), Special Stains, Digital Scanning, and Telepathology, each utilizing state-of-the-art technology and methodologies to provide detailed insights into disease pathology.
Ancillary Tests at BDL
Immunohistochemistry (IHC)
Immunohistochemistry (IHC) at BDL represents the convergence of pathology and immunology, offering a window into the cellular dynamics of diseases. Leveraging our access to over 80 antibodies, our IHC services provide unparalleled precision in the detection and localization of specific proteins within tissue sections. This capability is crucial in identifying the presence and extent of various cancers, as different tumors express unique markers that can be targeted for treatment.
At BDL, IHC is not just a test; it's a vital tool in the arsenal of personalized medicine. By revealing the molecular landscape of tumors, our IHC analyses guide oncologists in choosing the most effective targeted therapies, offering hope for better outcomes. The technique's specificity also aids in distinguishing between closely related conditions, ensuring accurate diagnoses.
Our commitment to excellence in IHC is supported by state-of-the-art technology and a team of dedicated professionals. Continuous advancements in our IHC protocols ensure that our services remain at the forefront of diagnostic precision, contributing significantly to the field of precision medicine and improving patient care strategies
Special Stains
Our repertoire of special staining techniques plays an indispensable role in the nuanced analysis of tissue samples. These specialized stains allow us to visualize features not apparent with conventional H&E staining, providing deeper insights into disease pathology. Our lab's extensive array of special stains includes, but is not limited to, Periodic Acid-Schiff (PAS) for fungi and mucosubstances, Ziehl-Neelsen for mycobacteria, and Masson's Trichrome for connective tissue, among others.
Each stain is carefully selected based on the suspected pathology, ensuring targeted and meaningful diagnostic information. For instance, our use of PAS stains is crucial in the detection of fungal infections and glycogen storage diseases, while the Ziehl-Neelsen stain is fundamental in identifying tuberculosis and other mycobacterial infections. Similarly, Masson's Trichrome stain provides essential data on the extent of fibrosis in liver and kidney diseases.
By offering a wide range of special stains, BDL empowers pathologists with the tools needed for a comprehensive tissue analysis. This meticulous approach to histopathology not only enhances our diagnostic precision but also significantly contributes to the formulation of accurate treatment plans, underlining our commitment to advancing patient care.
LIST OF SPECIAL STAINS AVAILABLE AT BIODYNAMICS LAB
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Alcian Blue PAS
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Azan Trichrome
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Giemsa
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Gomori Trichrome
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Grocott kit
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Hemognost perls
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Masson fontana
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Masson Trichrome
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Mucicarmine kit
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Orcein kit
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PAS kit
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Reticulin kit
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TB stain
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Warthin starry kit
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Diff-quike kit
In Situ Hybridization (ISH)
We are proud to introduce our In Situ Hybridization (ISH) services, a sophisticated diagnostic technique that complements our Immunohistochemistry (IHC) and Special Stains services. ISH is a powerful method for detecting specific nucleic acid sequences within tissue sections, providing critical insights into gene expression and genetic alterations. This technique is invaluable for understanding the molecular underpinnings of various diseases, including cancers and infectious diseases, by visualizing the localization of specific DNA or RNA sequences.
Utilizing state-of-the-art technology and protocols, our ISH services enable the precise identification of gene abnormalities and the expression patterns of critical biomarkers. This capability is essential for diagnosing genetic diseases, characterizing cancer subtypes, and identifying viral or bacterial infections at the molecular level. ISH's ability to reveal the genetic landscape of tissue samples significantly enhances the diagnostic accuracy and contributes to a more comprehensive understanding of disease processes.
Incorporating ISH into our suite of diagnostic services allows BDL to offer a more holistic approach to tissue analysis. By integrating ISH findings with the results from IHC and Special Stains, we provide a multi-dimensional view of disease pathology, enriching the diagnostic information available to oncologists, geneticists, and other healthcare providers. This enriched dataset supports the development of personalized treatment plans, ensuring targeted and effective therapies for patients.
Our commitment to delivering cutting-edge diagnostic services is exemplified by our ISH services. The BDL team, consisting of experienced pathologists and technologists, is dedicated to continually advancing our knowledge and capabilities in ISH, aiming to stay at the forefront of diagnostic innovation. Through our ISH services, we strive to contribute to the advancement of personalized medicine, improving patient outcomes through precise and comprehensive diagnostic insights.
Ancillary Services
Digital Scanning & Telepathology
In the realm of pathology, digital scanning represents a significant leap forward, and at BDL, it is a cornerstone of our diagnostic process. Through the conversion of traditional glass slides into high-resolution digital images, BDL harnesses the power of digital pathology to advance patient care. This state-of-the-art technology not only enhances the clarity and detail of pathological images but also introduces a new level of efficiency and accessibility to the diagnostic process.
Digital scanning at BDL allows for the meticulous examination of slides with advanced image analysis software, offering pathologists the ability to zoom in on areas of interest and assess fine details that might be missed under a conventional microscope. Furthermore, these digital images can be easily stored, cataloged, and retrieved, creating a valuable digital archive that improves case management and longitudinal studies.
One of the most transformative aspects of digital scanning is its capacity to support telepathology. By sharing digital images with experts around the globe, BDL facilitates rapid second opinions, collaborative research, and remote learning opportunities. This connectivity not only accelerates diagnostic turnaround times but also fosters a collaborative environment that enhances the quality of care provided to patients.
Aperio GT450
By Leica Biosystems
Our adoption of the Aperio GT450 Digital Scanner marks a significant advancement in our digital pathology capabilities. This high-throughput scanner is instrumental in transforming our Histopathology slides into high-definition digital images, setting new standards for speed, efficiency, and image quality in our diagnostic processes.
The Aperio GT450's state-of-the-art technology ensures rapid scanning of slides, significantly accelerating our workflow and reducing the time from specimen receipt to diagnostic reporting. Its exceptional imaging capabilities allow for the capture of detailed, true-to-life images, enhancing our pathologists' ability to conduct thorough analyses and make accurate diagnoses.
This scanner's reliability and precision are pivotal in our telepathology services, enabling us to share high-quality images with specialists worldwide for second opinions or collaborative studies. Moreover, the digital images produced are invaluable resources for research and educational purposes, providing a detailed visual record that can be easily accessed and studied.
By integrating the Aperio GT450 Digital Scanner into our diagnostic arsenal, BDL not only enhances the quality and efficiency of our services but also reinforces our commitment to leveraging cutting-edge technology for the betterment of patient care and medical science.
